Connect to a mixer

How do I connect my speakers to my mixer? What order should I connect my speakers?

You can choose to run the signal through the subs to the tops because that's the easiest and most consistent way to get the signal to both sets of boxes. You won't forget to adjust the level of the subs when you adjust the level of the tops.  (seen it happen way too often)  If you mix your instruments with subs on an aux, that's an obvious requirement for aux-fed subs.  

If you must have separate control of the subwoofer levels from the mixer, then you can run the subs from the auxes. (Always use two, never sum your subs to mono.) One thing you DON'T want to do if you run subs on aux sends is apply ANY filters to the aux outs. The signal going to the subs needs to be identical to the signal going to the tops, with the only separate adjustment being the level.

Here is a handy infographic showing a recommended setup for DJs who primarily control their setup through a DJ mixer, and through a mixing board. Live sound engineers should follow standard gain structure rules through their mixing console.